Document Details Document Type : Article In Journal  Document Title : The axenic cultivation of Leishmania donovani amastigotes زراعة الطور اللاسوطي لليشمانيا الدونوفانية في وسط خالي من الخلايا   Subject : Leishmania  Document Language : English  Abstract : Leishmania parasite cause a wide range of human disease from localized self-healing cutaneous lesions to fatal visceral disease. These parasites are characterized by having a non-motile form, Amastigotes, within the macrophage of the mammalian host and a motile form, promastigote, in the sand fly. Transformation of Promastigotes has been attracting considerable attention in studying the parasite-host interaction. It is the purpose of this article to review the transformation of Promastigotes to Amastigotes and the growth of the later form in cell free medium, i.e. axenically. Also, results of original work on axenic Amastigotes of Leishmania donovani are shown. The effect of temperature, pH and gas requirements on the transformation and further growth of Leishmania donovani axenic amastigotes are discussed.  ISSN : 1658-3175  Journal Name : Saudi Medical Journal  Volume : 20  Issue Number : 5  Publishing Year : 1420 AH 1999 AD  Article Type : Review Article  Added Date : Sunday, October 26, 2008  Researchers Researcher Name (Arabic) Researcher Name (English) Researcher Type Dr Grade Email هيثم أحمد زكائي Zakai, Haytham Ahmed Investigator Doctorate hzakai@kau.edu.sa بوا اندرو بيتس Bates, Paul Andrew Researcher Doctorate   مايكل تشانس Chance, Michael Researcher Doctorate   Files File Name Type Description  18286.pdf pdf   Back To Researches Page