Document Details

Document Type : Article In Journal 
Document Title :
Is Toxoplasma gondii IgG seropositivity a predisposing factor for infertility?
هل ايجابية المصل من الفئة ج لمقوسة جوندي عامل مهيء لقلة الخصوبة؟
 
Subject : Parasitology 
Document Language : English 
Abstract : Toxoplasmosis is a disease caused by an obligate intracellular protozoan parasite Toxoplasma gondii. Approximately one third of the world population is infected with this parasite. Several studies have examined the causes of human infertility in the Middle East. A high proportion of secondary infertility and a great contribution of the female factor was the major finding in most of these studies. In this study we aim to explore the relation between Toxoplasma gondii seropositivity and female infertile patients. Serum samples from 83 female patients visiting the infertility clinic and 57 normal prim gravid females attending the ANC clinic were collected during the year 2014. Serum samples were analyzed for anti-Toxoplasma IgG by chemiluminescent micro particle immunoassay (CMIA) technology. Patients visiting the infertility clinic aged from 18-40 years (x=29.7) while normal prim gravid females attending the ANC clinic aged from 18-38 (x=26.1). Of the 83 samples collected from patients visiting the infertility clinic, 15 samples were positive for anti-Toxoplasma IgG while only 2 samples (out of 57) collected from normal prim gravid females attending the ANC clinic were positive. There was a statistically significant correlation between positive anti-Toxoplasma IgG and infertility (p<0.01). We suggest considering the presence of anti-Toxoplasma antibodies in serum of young females as an indicator for possible future infertility. 
ISSN : 0976-7614 
Journal Name : Journal of Advanced Laboratory Research in Biology 
Volume : 4 
Issue Number : 2 
Publishing Year : 1436 AH
2015 AD 
Article Type : Article 
Added Date : Sunday, March 22, 2015 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
هيثم أحمد زكائيZakai, Haytham AhmedInvestigatorDoctoratehzakai@kau.edu.sa
مازن عابد بشارةBisharah, Mazin AbidResearcherDoctorate 

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